Clinical Sciences/Health Conditions
Courtney Frengopoulos, MD
Resident, Physical Medicine and Rehabilitation
McMaster University
Hamilton, Ontario, Canada
Aaida Ali, n/a
Student
University of Western Ontario
London, Ontario, Canada
Lauren Cormier, MD
Consultant Physiatrist
University of Western Ontario
London, Ontario, Canada
Michael WC Payne, MD
Associate Professor; Medical Director, Amputee Rehabilitation Program; Associate Research Director
Schulich School of Medicine and Dentistry, University of Western Ontario
London, Ontario, Canada
Indigenous peoples in Canada experience disproportionately high rates of diabetes and diabetes-related complications, including lower-extremity amputation (LEA). Although the epidemiology of LEA in these populations is well described, far less is known about rehabilitation outcomes, prosthetic use, or post-amputation challenges faced by Indigenous people. Understanding these factors is crucial for developing equitable and culturally safe rehabilitation pathways. The objective of this study was to describe the rehabilitation and prosthetic-related outcomes for rehabilitation in Indigenous peoples of Canada who have undergone LEA, and identify the challenges related to rehabilitation access and prosthetic fitting. There were 200 articles identified in the search, 25 underwent full-text review and four were included in the final review. Across these studies, 42 Indigenous participants were confirmed to have undergone LEA. Most amputations were unilateral transtibial, with diabetes and vascular disease being common etiologies. Participants were generally between 45 and 70 years of age. Functional outcomes varied: some achieved independent mobility, while others reported falls, gait-aid dependence, and limitations in daily activities. Compared to non-Indigenous participants, Indigenous individuals had similar frequency of prosthesis use but faced greater barriers, including socioeconomic disadvantage, shorter rehabilitation, geographic isolation, and limited access to follow-up services. Evidence describing prosthetic rehabilitation outcomes for Indigenous peoples in Canada is scarce, highlighting both meaningful functional gains and significant systemic barriers. Further community-led, culturally grounded research is urgently needed.
Design: MEDLINE, CINAHL, Scopus, Embase, and Web of Science were searched from inception through June 18, 2025 for this scoping review. Studies were included if they reported rehabilitation outcomes following amputation for Indigenous peoples in Canada.
Results:
Conclusion: