Neuromodulation and Biomarkers in Central Fatigue: Advances and Clinical Applications

Monday, May 18, 2026

2:30 PM - 3:30 PM PT

Location: 211

Ideal Audience:Physicians, Researchers, Residents/Fellows, Medical Students

Course Director(s)

Qing Mei Wang, MD, PhD

Director, Stroke Biological Recovery Laboratory
Spaulding Rehabilitation Hospital/Harvard Medical School

Speaker(s)

Xun Luo, MD (he/him/his)

Academician, European Academy of Natural Sciences; Academy Master Supervisor, Wenzhou Medical University
Wenzhou Medical University Big Health Development Institute
Xin Wang, PhD

Chief Physician, associate professor
Department of Rehabilitation Medicine, Northern Jiangsu People's Hospital , Yanzhou, China
Yuan Peng, MD

Associate Professor
Guangzhou First People's Hospital

Brief Session Description : This session explores emerging science and clinical strategies for managing central fatigue across conditions such as Long COVID, Lyme IACI, ME/CFS, multiple sclerosis, and post-concussive syndromes and stroke. Participants will examine recent advances in serum and neuroimaging biomarkers used to identify central fatigue mechanisms and guide treatment. The course also reviews non-invasive neuromodulation techniques (rTMS, tDCS, and VNS), highlighting their therapeutic potential and evidence base. Through case-based discussion and interactive engagement, attendees will gain practical tools to integrate biomarker insights and neuromodulation into patient care and research.

COI
Unless noted below there are none.
Qing Mei Wang, MD, PhD – Disclosed role as site principal investigator (NIH-funded research)

Session Objectives:

Upon completion of this program, participants will be able to identify key neuromodulation techniques used to target central fatigue, and discuss current definitions, mechanisms, risk factors, and emerging serum and neuroimaging biomarkers for identifying at-risk populations and potential treatment targets.
CanMEDS: Medical Expert. Health Advocate. Scholar.