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Final Program


Final Congress Guide

Therapeutics

1000 Section - Autologous platelet-rich plasma and extracorporeal electromagnetic shockwave therapy in pressure injury management after spinal cord injury: A case report

Wednesday, May 20, 2026
6:00 PM - 7:30 PM PT

    Presenting Author/Autor expositor(s)

  • xy

    xi yu, MD

    Attending doctor
    West China Hospital, Sichuan University
    Chengdu City, Sichuan Province, Sichuan, China (People's Republic)

    • Co-Author/Coautor(s)

  • LR

    Ling Ren, MD

    Attending doctor
    West China Hospital, Sichuan University
    Chengdu City, Sichuan Province, Sichuan, China (People's Republic)

    • Corresponding Author/Autor a quien dirigir la corr(s)

  • HH

    Hongchen He, MD

    Professor
    West China Hospital, Sichuan University
    Chengdu City, Sichuan Province, Sichuan, China (People's Republic)

Case Diagnosis: A 54-year-old female patient was diagnosed with T12 spinal cord injury（ASIA-A）after a vehicle accident 5 years ago. A stage-3 pressure injury developed on her left ischial tuberosity area. 

Case Description: Before PRP wound treatment, we treated the patient with extracorporeal electromagnetic shockwave therapy (ESWT) using a Dornier Aries U (Dornier MedTech GmbH, Wessling, Germany) electromagnetic device three times weekly with application of 2000 shockwaves at 6 Hz, at an energy density of 2.0-3.4mJ/mm2. After ESWT, we applied autologous PRP wound treatment. The PRP was manufactured by centrifugation. In total, 40ml of peripheral blood was collected and centrifuged to acquire PRP 5ml. PRP gel was formed by adding thrombin. Then, PPR injections were performed to the rim and the center of the wound. The PRP gel was placed on the surface of the wound. PRP wound treatment was also three times a week, along with ESWT. No further surgical or invasive treatment was required.

Discussions:

PRP contains a variety of cytokines, such as VEGF, PDGF, and TGF-β, which effectively promote angiogenesis and cell proliferation, thereby accelerating the wound healing process. ESWT primarily exerts its effects through local pressure and cavitation effects. It improves microcirculation, activates the release of growth factors, enhances cellular metabolic activity, and regulates signaling pathways associated with bone healing.

The combination of PRP and ESWT in patients with SCI complicated by PIs demonstrates significant synergistic potential in promoting wound healing. Wound measurements along with infrared thermography results confirmed therapeutic effects in this case. PRP provides key bioactive factors for tissue repair, while shockwaves further optimize the local microenvironment through mechanobiological mechanisms, enhancing cellular responsiveness to growth factors. 

Conclusions:

In conclusion, the favorable wound healing effect of PPR and ESWT on PI for SCI patient make it feasible clinical rehabilitation option. Further controlled studies are needed to evaluate the superior ESWT parameters.