400 Section - Efficacy of Cognitive Behavioral Therapy in Middle-aged Men with Schizophrenia and Comorbid Sleep Disorders

This study aimed to investigate the efficacy of cognitive behavioral therapy (CBT) in middle-aged men with schizophrenia and comorbid sleep disorders, and to analyze the changes in patient symptoms and sleep quality before and after treatment. 

Design:

 A retrospective cohort study design was used to screen middle-aged men with schizophrenia and comorbid sleep disorders admitted to Three Gorges Central Hospital of Chongqing University from January 2023 to December 2024. A total of 33 patients who received CBT were included in treatment group, while the remaining 39 patients who received conventional therapy were assigned to control group. Clinical data of the two groups were compared using SPSS.

Results:

Twelve weeks after treatment, the total scores of the positive and negative syndrome scale (PANSS), pittsburgh sleep quality index (PSQI), self-rating depression scale (SDS), self-rating anxiety scale (SAS), and sleep efficiency in the two groups were 57.2±8.1 vs 72.3±7.5, 6.2±1.5 vs 11.4±1.8, 41.5±6.3 vs 54.7±7.0, 42.9±8.1 vs 56.6±7.5 and (78.9±9.2)% vs (66.1±8.5)%, the differences were statistically significant (P< 0.05). The univariate logistic regression analysis indicated that CBT was a significant factor in improving schizophrenia symptoms and enhancing sleep quality, with OR of 3.56 (95% CI, 1.85-6.83) and 4.12 (95% CI, 2.32-7.31), P< 0.05. 

Conclusion:

CBT demonstrated significant efficacy in middle-aged men with schizophrenia and comorbid sleep disorders, improving not only the patients’ psychiatric symptoms but also significantly enhancing sleep quality.