600 Section - Sleep disturbance in adults with cerebral palsy: a clinic based sample

A convenience sample of adults with CP was enrolled during routine clinic visits. The Gross Motor Function Classification System (GMFCS) level was determined by clinicians. Weight and waist/hip ratio were measured using standard techniques. Grip strength for both hands was evaluated with a Jamar Hydraulic Hand Dynamometer, using the highest score from six trials. Participants completed portions of the Patient-Reported Outcomes Measurement Information System (PROMIS) surveys regarding sleep disturbance and pain, as well as questions about medical history.

Results:

Ninety-one subjects participated (mean age 39.2 years, range 19–75; 55% female). GMFCS distribution was: I 22%, II 30.8%, III 14.3%, IV 25.3%, V 3.3%, missing 4.3%. Overall, 14% reported sleep quality as poor or very poor, 36% as fair, 45% as good, and 5% as very good. 41% used sleep aids (devices or medication). The mean PROMIS sleep disturbance score was 54.2 (SD 3.2). Pain was present in 71.4% of subjects at the time of assessment. Significant associations were found between sleep disturbance and pain (p = .02) and a history of respiratory infection or asthma (p = .02). There was a weak, non-significant association between sleep disturbance and younger age (r=-0.19, p=0.07), higher functioning GMFCS level (r=-0.19, p=0,08) and history of anxiety (0.18, p=0.09). Grip strength and anthropometric measures were not associated with sleep disturbance.

Conclusion: Sleep disturbance is common among adults with CP, particularly those with pain and respiratory conditions. Routine screening for sleep problems is recommended in adults with CP.