1000 Section - Ultrasound-Guided Pes Anserine Bursitis Injection Choices: Prolotherapy or Oxygen-Ozone or Corticosteroid

Objectives : Pes anserine bursitis is the most common cause of periarticular knee pain. The aim of the study was to evaluate the efficacy of three local injections with different materials.

Design: The enrolled patients were randomly allocated to three groups to receive different interventions (Prolotherapy or Oxygen-Ozone or Corticosteroid). Outcome measures included pain severity using the visual analog scale and the Western Ontario and McMaster Universities osteoarthritis index that was evaluated before the intervention, 1 and 8 weeks after that.

Results: This trial was performed on 72 participants, with male-to-female ratio of 0.14 and with a mean age of 61.49 ± 9.35 years. Corticosteroids in the first group, oxygen-ozone in the second group, and dextrose 20% in the third group, were injected into the pes anserine bursa under ultrasound guidance. Interaction between time and group showed a statistically significant improvement in visual analog scale and Western Ontario and McMaster Universities Arthritis Index ( P ≤ 0.05) in favor of corticosteroids and oxygen-ozone groups after one week and in favor of oxygen-ozone and prolotherapy groups after 8 weeks.

Conclusion: All three treatment options are effective for patients with pes anserine bursitis. This study showed that the effects of oxygen-ozone injection and prolotherapy last longer than those of corticosteroid injection.