1000 Section - Study on the Application of Evoked Potentials in the Evaluation of Rehabilitation Efficacy in Patients with Chronic Disorders of Consciousness

Wednesday, May 20, 2026

6:00 PM - 7:30 PM PT

Presenting Author/Autor expositor(s)

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chenxia xue, MD

Ph.D.
Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
Shanghai, Shanghai, China (People's Republic)

Co-Author/Coautor(s)

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chen shu, MD

Ph.D.
Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
Shanghai, Shanghai, China (People's Republic)
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chao zhang, MD

Ph.D.
Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
Shanghai, Shanghai, China (People's Republic)
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lei chen, MD

Ph.D.
Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
Shanghai, Shanghai, China (People's Republic)

Corresponding Author/Autor a quien dirigir la corr(s)

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hongxiang liu, MD

Ph.D.
Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)
Shanghai, Shanghai, China (People's Republic)

Objectives : To evaluate the value of Brainstem Auditory Evoked Potentials (BAEP) and Somatosensory Evoked Potentials (SEP) in monitoring rehabilitation efficacy among patients with prolonged disorders of consciousness (pDoC)

Design: Thirty patients with prolonged Disorders of Consciousness (pDoC) were enrolled from the Intensive Rehabilitation Department of Shanghai Yangzhi Rehabilitation Hospital between October 2023 and March 2025. All patients received conventional awakening-oriented rehabilitation interventions, including exercise training, multisensory stimulation, median nerve stimulation (MNS), and acupuncture.. Before treatment and 4 weeks after treatment, assessments using the Coma Recovery Scale-Revised (CRS-R), Glasgow Coma Scale (GCS), SEP, and BAEP were conducted respectively.

Results: Post-treatment CRS-R and GCS significantly improved (P < 0.05). SEP showed decreased bilateral N20 latencies and increased amplitudes (P < 0.05). BAEP revealed significantly reduced bilateral wave-I latency and right wave-III latency (P < 0.05), while other changes in latencies and interpeak intervals were not significant (P > 0.05).

Conclusion:

The improvement trends of SEP and BAEP were consistent with the behavioral scores of the CRS-R and GCS, suggesting that evoked potentials can provide objective, physiological-dimensional evidence for evaluating the rehabilitation efficacy in patients with prolonged Disorders of Consciousness (pDoC).