300 Section - Tibial Nerve Amplitude as an Electrophysiological Predictor of Sarcopenia

Wednesday, May 20, 2026

6:00 PM - 7:30 PM PT

Presenting Author/Autor expositor(s)

A�

Ahmet Furkan Çolak, N/A, MD

MD
Hacettepe University Faculty of Medicine, Department of Physical and Rehabilitation Medicine
Ankara, Ankara, Turkey

Co-Author/Coautor(s)

BY

Berkay Yalçınkaya, N/A, MD

MD
Hacettepe University Faculty of Medicine, Department of Physical and Rehabilitation Medicine
Ankara, Ankara, Turkey
MK

Murat Kara, N/A, MD

MD, Professor
Hacettepe University Faculty of Medicine, Department of Physical and Rehabilitation Medicine
Ankara, Ankara, Turkey
Levent Özçakar, N/A, MD

MD, Professor
Hacettepe University Faculty of Medicine, Department of Physical and Rehabilitation Medicine
Ankara, Ankara, Turkey

Objectives : This study aimed to evaluate tibial nerve motor amplitude in sarcopenia and to highlight the potential predictive/diagnostic value of tibial nerve assessment for sarcopenia.

Design: A total of 200 postmenopausal women aged ³50 years were included. All participants were assessed for sarcopenia using the ISarcoPRM diagnostic algorithm, which incorporates hand grip strength, chair stand test (cut-off values being 19 kg and 12 sec, respectively), and ultrasound-based quadriceps femoris muscle thickness measurements. The latter was adjusted for body mass index, with < 1.0 indicating low muscle mass. Tibial nerve motor amplitude was obtained using electrodiagnostic testing. Binary logistic regression was used to identify independent predictors of sarcopenia.

Results: A total of 83 (41.5%) were diagnosed with sarcopenia. Compared to controls, the sarcopenia group was older and had higher body mass index and higher frequency of hypertension (all p< 0.001). Tibial nerve amplitude was reduced in women with sarcopenia (p< 0.001). Regression analysis revealed that age (OR=1.082, 95% CI: 1.003-1.166, p=0.041), body mass index (OR=1.135, 1.035-1.246, p=0.007), hypertension (OR=3.169, 1.103-9.110, p=0.032), and tibial nerve amplitude (OR=23.901, 7.888-72.419, p< 0.001) were independent predictors of sarcopenia.

Conclusion: Tibial nerve amplitude is a powerful electrophysiological predictor of sarcopenia. This finding highlights the potential value of incorporating tibial nerve assessment for sarcopenia evaluation in postmenopausal women.